914 children were treated in hospital for drug or alcohol-related illnesses last year.
According to freedom of information figures, nearly two thirds were girls.
The conditions include drug or alcohol poisoning, a mental health disorder due to substance misuse, and new-born children affected by their mothers' use of drugs or alcohol.
The figures are spread throughout the country and of those hospitalised last year, 228 children were aged less than nine years old. 686 children were aged between 10 and 17 - with over twice as many girl as boys.
Gifted Stitches A Future Plan For Wicklow's World-Record Knitted Map
Have You Seen Missing Alex Kenna?
Greater Local Link Demand Drives New 183 and 895 Bus Route Services For Wicklow Users
Cliff Walk Committee Expanded To Include Local Representives
Greystones Welcomes News Of Long-Awaited Garda Station Refurbishment