St Gerard’s in Bray ranks 10th overall, the top mixed fee paying school on the list, up 20 places on 2019 with 89% progressing to third level courses.
Colaiste Íosagáin in Booterstown, south Dublin is the top secondary school in the country for the first time.
The new Sunday Times Best Schools Guide shows the Gaelcholáiste has beaten off Limerick's Laurel Hill Coláiste FCJ which falls to second.
Girls' schools make up eight places in the top ten, while South Dublin's fee-paying Gonzaga College is third overall and is Ireland's top boys' school.